Hyaluronic Acid – The Ultimate Skin Hydrator

Hyaluronic Acid (HA) is a naturally occurring humectant found in the skin, joints, and connective tissues. It has an exceptional ability to retain moisture, making it a key ingredient in skincare.

Discovery & Manufacturing

Hyaluronic Acid was first identified in 1934 by Karl Meyer and John Palmer at Columbia University in New York City, USA.

Initially, it was extracted from the vitreous humor of cow eyes, but modern production uses fermentation. Today, the largest production hubs for Hyaluronic Acid are in China, Japan, and the United States, where it is synthesized for cosmetics, pharmaceuticals, and medical applications.

Chemical Structure & Function

Hyaluronic Acid is a glycosaminoglycan (GAG) composed of repeating units of D-glucuronic acid and N-acetyl-D-glucosamine. This unique structure allows it to bind water molecules, ensuring hydration and elasticity in the skin.

Molecular Weight Penetration Depth Skin Benefits
High Molecular Weight (1,000 - 1,500 kDa) Stays on the surface Forms a moisture barrier, reduces dehydration
Medium Molecular Weight (200 - 800 kDa) Mid-layer penetration Improves elasticity, reduces fine lines
Low Molecular Weight (50 - 200 kDa) Deep penetration Deep hydration, plumps skin from within
Oligo-Hyaluronic Acid (<50 kDa) Deepest penetration Boosts skin repair, increases collagen production

Fun Facts About Hyaluronic Acid

Fun Fact #1
Hyaluronic Acid was first extracted from the vitreous humor of cow eyes before scientists discovered bacterial fermentation.
Fun Fact #2
The human body naturally contains about 15g of Hyaluronic Acid, with half of it in the skin.
Fun Fact #3
Some of the longest-lived people in the world (in Yuzurihara, Japan) consume foods high in Hyaluronic Acid!

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